ICSNPathway -> Result

Download result file Parameters

Job Name		Email
Most significant SNPs		GWAS SNP P-value file
P-value -> -log₁₀(P-value)	false	Population
LD CutOff	:	Distance	kb
Rule of mapping SNPs to genes		FDR cutoff for PBA
Pathway/Gene Set size(min)		Pathway/Gene Set size(max)
Pathway/Gene Set

Hypothesis

Candidate causal SNPs

Candidate causal SNP	Functional class	Gene	Candidate causal pathway^a	-log₁₀(P)^b	In LD with	r²	D'	-log₁₀(P)^c

^a The number indicates the index of pathways, which are ranked by their statistical significance (FDR).
^b -log₁₀(P) for candidate causal SNP in original GWAS. '-' denotes that this SNP is not represented in the original GWAS.
^c -log₁₀(P) for the SNP (which candidate causal SNP is in LD with) in original GWAS.

Candidate causal pathways

Index	Candidate causal pathway	Description	Nominal P	FDR